Mark Stidham:  

CLASS OF 1971
Mark Stidham's Classmates® Profile Photo
Costa mesa, CA

Mark's Story

Life Married '79, grad. UCI '75 & UCR '80 Ph.D. in biochem. 3 children born in '80, '83, & 88. Lived in the Princeton, NJ area from '83 to '02, and then moved to San Diego. I am a research director in a small biotech firm. I am in contact with Scott Endsley, Don Paige, Michele Sarlat, Brian West, and Lee Engdahl. I have good memories of the high school years, even though I felt invisible for the most part. What about me would surprise everyone at a reunion is...that I married well. My social development lagged in high school and even in college, and it was not until I was 23 that I began to feel confident. I married when I was 25, but even with the late blooming, I understood that a good marriage required total acceptance and support on both parties along with an interest in learning and continual growth. Perhaps the other aspect that would surprise certain people who knew me is my complete rejection of the church. In high school, I felt in a small minority of people who were active in churches. Soon after high school, I awakened to the truth in my view and left religion. I have noticed that many classmates have gone the other way and have become centered on religion. I can only say I am at peace and 'believe' society would benefit from a focus on behavior rather than on the premise of behavior. This is pretty heavy stuff for a Classmates column I guess. Not surprising to anyone would be my career in science. I did not get my first real job until I was 29, but I have made a good living as a biochemist. The children are almost grown, and though the career is in hyperdrive at the moment, I am looking forward to starting a new chapter somehow. Don't know what it will be, but it will include more writing, music, and volunteer work. In high school and college, I had a job opening up Mesa High gym at night for recreational activities. I ran a few basketball leagues and kept the score books, feeding them in the summer time to a news-starved Daily Pilot. A guy named Jim Erwin was head of Costa Mesa Parks and Recreation, and I figured he had the best job possible. I thought maybe that I would work in a job like that, but at UC Irvine in my junior year, I had my first biochemistry class, and I was hooked. A short 7 years later, I had a Ph.D. in the subject. After high school, Dennis Ciolli and I applied for jobs at Disneyland. I started there as a bus boy at the Riverbelle Terrace (formerly, Aunt Jemimah's Pancake House) during s...Expand for more
pring break in 1972. I worked that summer and the next two at Disneyland. Dennis continued on with Disney after he got his accounting degree from Cal State Fullerton. He retired from there after 35 years. Amazing. I was best man in his wedding in 1977. Now I am enjoying life in San Diego. After living 18 years in the Princeton, NJ area, the good job I had at American Cyanamid went away with the sale of the company to BASF. I had achieved some success in high throughput lab automation and was able to secure a job as a field sales consultant for Zymark, a leading lab automation company. We moved to San Diego, and Marcus started high school at Rancho Bernardo HS. The job was okay but I wasn't really going anywhere in my career. Sales was not as lucrative as advertised, and the biotech bubble was beginning to burst. From out of the blue came an ex-Cyanamid colleague John Finn. He had left Cubist Pharmaceuticals in Boston and was relocating to San Diego to start a new antiinfective drug discovery company. I interviewed and got the job without a problem. Within 3 months, the company folded, but John had the notion of starting another company based on transferring some NIH SBIR grants. The request went through for one grant. We had $2.7MM over 3 years to make a go of it. John concocted a '5-10 plan' to enable the funding to work. The six of us who joined took a 5% pay cut and a 10% pay deferral. This 15% hit still put me ahead of my Zymark (now Caliper LS) earnings. Also, house prices had sky-rocketed in the two years since the move, so we refinanced to get additional cushion in case Rx3 Pharmaceuticals failed. In the next years, we secured another $2MM in grant money, and even another $3MM grant. In the mean time, a group of venture capitalists invested $20MM, and we became Trius Therapeutics. That was in 2007. It is 2010 we went public, and we are listed on the NASDAQ as TSRX. We -licensed a drug from Dong-A Pharmaceuticals (torezolid, now known as tedizolid), and we progressed this through Phase 1 and Phase 2. Now we are in Phase 3 trials. My job has changed to government contract management, and our major project has progressed to IND-enabling stage. October 2015 - The drug was approved (Sivextro) and is marketed by new owner Merck. Company sold in 2013, lay-off/retirement in 2014. Knee replacement surgery 13 months ago was transformative. Best thing I've done in a long time. Two new startups. Pretty happy these days
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Photos

Mark Stidham's Classmates profile album
Mark Stidham's Classmates profile album
Rx3 Pharmaceuticals 2007
Grandson
Grandson Hunter Gibson
team photo tour de cure
2009 Tour de Cure San Diego
December 2007
Mark and Diana in Kauai 2007
Rx3 Pharmaceuticals 2007
scan
family on stairs
glendelblues1978
mark and diana ii
Wedding of my eldest daughter Elizabeth Nov 06

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